My family and I (My parents, adult siblings, and sibling-in-laws) all stayed here and had plenty of space. the setup includes 4 individual bedrooms with connected bathrooms, and a shared living room / kitchen. The kitchen was a little small if you wanted to use it to cook, but it was great for our purposes. Also, the air conditioning worked great, and was a great relief during the august heat.
Location was also awesome, It was very close to the Vatican (5 minute walk). We were able to walk everywhere from this location - even all the way to the Colosseum!
Francesca was an amazing host. She helped us arrange transportation to the cruise terminal, let us drop off our bags before check in so we didn't have to lug them around town, allowed us to check in early, and was extremely helpful with recommendations and advice.
I highly recommend this place to anyone who wants to visit Rome and has a larger group!