De Soto, Missouri holiday accommodation: short-term house rentals & properties

Scroll through and select from holiday rentals in De Soto to find one that's perfect for your trip. Holiday homes offer the amenities that you expect for your stay with friends, family or just your pet, such as a fireplace and a washer and dryer. At the end of the day, you're sure to find a property to rent to meet everyone's needs, including a place that's non-smoking or offers accessibility.

Find spaces that suit your style

House

Condo/Apartment

Find the best place to stay - De Soto

Secluded cabin on private property

Sleeps 8 · 2 bedrooms · 2 bathrooms

Beautiful 2BD condo in lakefront resort with lots of outdoor onsite activities

Sleeps 6 · 2 bedrooms · 2 bathrooms

Cabin Springs. Escape to the quiet country. Fish, hike, kayak, see the stars.

Sleeps 8 · 4 bedrooms · 3 bathrooms

Peace of mind
Our Book with Confidence Guarantee gives you 24/7 support
More quality time
From booking to staying, the whole process is simple and enjoyable
All the privacy of home
Enjoy full kitchens, laundry, pools, gardens and more
More for less
More space, more privacy, more amenities — more value

Choose a holiday rental for your De Soto getaway

Learn about the unique charm of De Soto with a stay in a holiday home rental. One of the city's many top draws is its restaurants. With a holiday rental, you get a home away from home – many rentals offer full kitchens and outdoor grills for some home cooking.

Activities and attractions in and around De Soto

Are you looking for things to do during your stay? Venture out of your cosy holiday rental and experience everything that makes De Soto a fun spot to go on holiday. Here are some of the top attractions to put on your list, all within 30 miles (48.2 km) of the city centre:

Villa Antonio Winery (10.6 mi / 17 km)
Bonne Terre Mine (14.9 mi / 24 km)
LaChance Winery (18.8 mi / 30.2 km)
Crown Pointe Golf Club (23.3 mi / 37.5 km)
Persimmon Ridge Winery (14.8 mi / 23.8 km)
Fore Honor Golf Course (16.6 mi / 26.7 km)

Exploring the natural landscape of De Soto

Whether you're an adventurous traveller or just want to spend some time taking in the scenery, De Soto is a great place to spend some time outside. These are some of the area's noteworthy natural features, all within 30 miles (48.2 km) of the city centre:

Lake Louise (9.9 mi / 16 km)
Bonne Terre Mine (14.9 mi / 24 km)
Mastodon State Historic Site (19 mi / 30.6 km)
Columbia Park (20.9 mi / 33.7 km)
Big River (24.5 mi / 39.4 km)
Victoria Glaces Conservation Area Trailhead (4.4 mi / 7.1 km)

Transport to and around De Soto

Fly into St. Louis, MO (SUS-Spirit of St. Louis), the closest airport, located 36.5 mi (58.8 km) from the city centre. If you're unable to find a flight that fits your schedule, you could also fly into Lambert-St. Louis International Airport (STL), which is 42.9 mi (69 km) away.

Frequently asked questions

How much does it cost to rent a holiday home in De Soto?

The average price for a holiday home in De Soto is determined by several factors, such as time of year, length of stay and property type. Whether you’re looking for a sprawling villa with lots of bedrooms or a quaint cabin ideal for just you and the kids, just enter your dates of travel to view stays with exceptional value.

How much does it cost to rent a beach house in De Soto?

The average price for a holiday home by the beach in De Soto depends on when you’re going and the size and type of property you’re searching for. You can find prices easily and quickly on Stayz by entering your dates of travel. Then use the handy filters to choose the number of bedrooms and amenities essential to you, like air conditioning, a pool and WiFi.

What are the top attractions for families in De Soto?

Have a fun day out with the kids at Victoria Glaces Conservation Area Trailhead. This top attraction is within easy reach of the heart of De Soto.

How old do you have to be to rent a holiday home in De Soto?

The minimum age is generally 16, 18 or 21. It can differ from one property to another on Stayz, so look at the rules of your preferred De Soto holiday home before making a booking.

How long can I rent a holiday home in De Soto for?

It’s really down to the De Soto property. To view a list of options offering extended stays, simply type your dates and number of guests into the Stayz search page. You can enjoy having the entire property to yourself, along with the comforts of home like a fully-equipped kitchen, air conditioning and an outdoor space where your little ones can play. Keep your eyes open for any long-term stays that offer weekly or monthly discounts.